Irem Ünalan, M. Sc.
Bioactive Scaffolds Containing Essential Oils for Tissue Engineering Applications
Betreuer: Prof. Dr.-Ing. habil. Aldo R. Boccaccini
Herbal medicines based on plant extracts such as rosemary, peppermint, lavender, lemongrass, cinnamon, thyme and grape seed have been used to accelerate the wound healing process since ancient times due to their anti-inflammatory, antimicrobial, antibacterial, antiviral, and antifungal properties . This research project aims to investigate new strategies for design, development and characterization of essential oil-based biodegradable polymeric scaffolds for wound healing process. The combination of essential oil with polymers to improve antibacterial potential of the scaffolds will be examined. The obtained materials will be characterized in terms of surface and mechanical properties, antibacterial activity, and biological compatibility in order to assess their suitability for enhancing the wound healing process.
Bakkali, F., et al., Biological effects of essential oils–a review. Food and chemical toxicology, 2008. 46(2): p. 446-475.
Physical and Antibacterial Properties of Peppermint Essential Oil Loaded Poly (epsilon-caprolactone) (PCL) Electrospun Fiber Mats for Wound Healing
In: Frontiers in Bioengineering and Biotechnology 7 (2019), Art.Nr.: 346
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Evaluation of electrospun poly(ε-caprolactone)/gelatin nanofiber mats containing clove essential oil for antibacterial wound dressing
In: Pharmaceutics 11 (2019), Art.Nr.: 570
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Bioactive glass (45S5)-based 3D scaffolds coated with magnesium and zinc-loaded hydroxyapatite nanoparticles for tissue engineering applications
In: Colloids and Surfaces B: Biointerfaces 182 (2019), Art.Nr.: 110346
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Bioactıve Glass-Polymer Nanocomposites for Bone Tıssue Regeneration Applicatıons: A Revıew
In: Advanced Engineering Materials (2019), Art.Nr.: 1900287
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