Irem Ünalan

Irem Ünalan, M. Sc.

Department Werkstoffwissenschaften (WW)
Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)

Raum 01.117
Ulrich-Schalk-Straße 3
91056 Erlangen

Telefon: +49 9131 85-69612
Faxnummer: +49 9131 85-28602
E-Mail: irem.unalan@fau.de
Webseite: http://www.biomat.techfak.uni-erlangen.de

Doktorandin

Bioactive Scaffolds Containing Essential Oils for Tissue Engineering Applications

Betreuer: Prof. Dr.-Ing. habil. Aldo R. Boccaccini

Herbal medicines based on plant extracts such as rosemary, peppermint, lavender, lemongrass, cinnamon, thyme and grape seed have been used to accelerate the wound healing process since ancient times due to their anti-inflammatory, antimicrobial, antibacterial, antiviral, and antifungal properties [1]. This research project aims to investigate new strategies for design, development and characterization of essential oil-based biodegradable polymeric scaffolds for wound healing process. The combination of essential oil with polymers to improve antibacterial potential of the scaffolds will be examined. The obtained materials will be characterized in terms of surface and mechanical properties, antibacterial activity, and biological compatibility in order to assess their suitability for enhancing the wound healing process.

[1]Bakkali, F., et al., Biological effects of essential oils–a review. Food and chemical toxicology, 2008. 46(2): p. 446-475.

2022

Mutlu N., Kurtuldu F., Ünalan I., Neščáková Z., Kaňková H., Galusková D., Michálek M., Liverani L., Galusek D., Boccaccini AR.:
Effect of Zn and Ga doping on bioactivity, degradation, and antibacterial properties of borate 1393-B3 bioactive glass
In: Ceramics International (2022)
ISSN: 0272-8842
DOI: 10.1016/j.ceramint.2022.02.192

2021

Chotchindakun K., Pekkoh J., Ruangsuriya J., Zheng K., Ünalan I., Boccaccini AR.:
Fabrication and characterization of cinnamaldehyde-loaded mesoporous bioactive glass nanoparticles/phbv-based microspheres for preventing bacterial infection and promoting bone tissue regeneration
In: Polymers 13 (2021), Art.Nr.: 1794
ISSN: 2073-4360
DOI: 10.3390/polym13111794
Coelho SAR., Almeida JC., Ünalan I., Detsch R., Miranda Salvado IM., Boccaccini AR., Fernandes MHV.:
Cellular Response to Sol-Gel Hybrid Materials Releasing Boron and Calcium Ions
In: ACS Biomaterials Science and Engineering (2021)
ISSN: 2373-9878
DOI: 10.1021/acsbiomaterials.0c01546
Ünalan I., Boccaccini AR.:
Essential oils in biomedical applications: Recent progress and future opportunities
In: Current Opinion in Biomedical Engineering 17 (2021), Art.Nr.: 100261
ISSN: 2468-4511
DOI: 10.1016/j.cobme.2021.100261
Ünalan I., Fuggerer T., Slavik B., Büttner A., Boccaccini AR.:
Antibacterial and antioxidant activity of cinnamon essential oil-laden 45S5 bioactive glass/soy protein composite scaffolds for the treatment of bone infections and oxidative stress
In: Materials Science and Engineering C 128 (2021), Art.Nr.: 112320
ISSN: 0928-4931
DOI: 10.1016/j.msec.2021.112320

2019

Dittler ML., Ünalan I., Grünewald A., Beltrán AM., Grillo CA., Detsch R., Gonzalez MC., Boccaccini AR.:
Bioactive glass (45S5)-based 3D scaffolds coated with magnesium and zinc-loaded hydroxyapatite nanoparticles for tissue engineering applications
In: Colloids and Surfaces B: Biointerfaces 182 (2019), Art.Nr.: 110346
ISSN: 0927-7765
DOI: 10.1016/j.colsurfb.2019.110346
Erol-Taygun M., Ünalan I., Idris MIB., Mano JF., Boccaccini AR.:
Bioactıve Glass-Polymer Nanocomposites for Bone Tıssue Regeneration Applicatıons: A Revıew
In: Advanced Engineering Materials (2019), Art.Nr.: 1900287
ISSN: 1438-1656
DOI: 10.1002/adem.201900287
Ünalan I., Endlein SJ., Slavik B., Büttner A., Goldmann W., Detsch R., Boccaccini AR.:
Evaluation of electrospun poly(ε-caprolactone)/gelatin nanofiber mats containing clove essential oil for antibacterial wound dressing
In: Pharmaceutics 11 (2019), Art.Nr.: 570
ISSN: 1999-4923
DOI: 10.3390/pharmaceutics11110570
Ünalan I., Slavik B., Büttner A., Goldmann W., Frank G., Boccaccini AR.:
Physical and Antibacterial Properties of Peppermint Essential Oil Loaded Poly (epsilon-caprolactone) (PCL) Electrospun Fiber Mats for Wound Healing
In: Frontiers in Bioengineering and Biotechnology 7 (2019), Art.Nr.: 346
ISSN: 2296-4185
DOI: 10.3389/fbioe.2019.00346