Gastdoktorandin (Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, China)
Development of hybrid and composite hydrogels based on the bioactive glass for bone tissue regeneration
Betreuer: Dr. Kai Zheng, Prof. Aldo R. Boccaccini
Hybrid or multimaterial hydrogels with organic and inorganic components are promising materials commonly used to promote bone regeneration . However, the wide application of composite materials may be compromised if they exhibit poor interfacial compatibility . Modifying organic or inorganic components can improve interfacial compatibility and consequently enhance the properties of hybrid hydrogels . In this project, hybrid and composite hydrogels based on bioactive glasses (BGs) and natural polymers (e.g., ADA-GEL, chitosan) will be developed following previous approaches  established in our Institute. In-depth physiochemical characterization and biological tests will be performed. Optimal components of hybrid (or composite) hybrogels will be selected to promote bone tissue regeneration.
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 Q. Lu et al., Inorganic-organic gel electrolytes with 3D cross-linking star-shaped structured networks for lithium ion batteries. Chemical Engineering Journal 393, (2020).
 A. Leite, et al., Bioplotting of a bioactive alginate dialdehyde-gelatin composite hydrogel containing bioactive glass nanoparticles. Biofabrication 8, 035005 (2016).