Gaststudentin, Universidad Francisco de Vitoria, Madrid, Spain
Essential oil incorporated polycaprolactone-based electrospun nanofibers for antibacterial wound healing
Betreuer: Irem Unalan, Prof. Aldo R. Boccaccini
Bacterial infection in wound healing is a critical health concern . In recent years, the use of natural antibiotic-free agents such as phytotherapeutics has been of renewed interest to suppress bacterial infection, including work in the Erlangen Institute of Biomaterials [2,3]. This project aims to overcome the contamination problem in the wound healing process by investigating natural phototherapeutic agents. For this propose, essential oil (EO) incorporated- polycaprolactone based electrospun nanofibers will be fabricated and characterized. Physico-mechanical behavior, antibacterial activity and biocompatibility will be investigated in detail as function of EO content.
 S. Homaeigohar, A.R. Boccaccini, Antibacterial biohybrid nanofibers for wound dressings, Acta Biomaterialia 107 (2020) 25-49.
 I. Unalan, et al., Evaluation of electrospun poly(ε-caprolactone)/gelatin nanofiber mats containing clove essential oil for antibacterial wound dressing, Pharmaceutics 11 (2019) 570.
 I. Unalan, et al., Physical and Antibacterial Properties of Peppermint Essential Oil Loaded Poly(ε-caprolactone) (PCL) Electrospun Fiber Mats for Wound Healing, Front Bioeng Biotechnol. 7 (2019) 346.