Fabrication of porous bioactive glass scaffolds incorporating plant-derived antibacterial agents
Betreuer: Marcela Arango Ospina, Prof. Dr.-Ing. habil. Aldo Boccaccini
The relatively new approach of combining herbal medicine or phytotherapeutics with biomaterials is a promising area of research. Especially bioactive glasses are interesting materials for bone regeneration due to their ability to not only replace, but also regenerate bone defects, which relies on their bioactivity and biodegradability . There are emerging studies on the combination of bioactive glasses with natural plant-derived antibacterial agents .
This bachelor thesis aims to prepare porous bioactive glass scaffolds for bone regeneration with a coating of the natural protein zein  and the addition of plant-derived antibacterial molecules. The idea of the coating is to improve the mechanical properties of the brittle glass scaffolds and to benefit from the antibacterial, antiseptic and anti-inflammatory effect of phytotherapeutic agents . The scaffolds will be characterized in terms of mechanical properties, bioactivity and antibacterial effect.
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