Ehemaliger Gaststudent (Warsaw University of Technology, Poland)
Zein particles as drug delivery systems
Supervisors: Zoya Hadzhieva, Prof. Dr.-Ing. habil. Aldo R. Boccaccini
There is a growing need for developing new drug carriers for drug delivery applications. One such carrier might be drug-loaded polymeric particles, in which the drug is encapsulated in a hydrophobic polymeric matrix that serves as a drug carrier . Among many materials used as drug carriers biopolymers draw attention, thanks to their biocompatibility and biodegradability . One such polymer is zein – a hydrophobic protein derived from corn. Different molecules obtained from natural resources such as green tea and coffee are being considered as phytotherapeutic agents. Some natural compounds exhibit anti-cancer properties . In this study, zein particles loaded with natural drugs are being manufactured. The obtained drug delivery systems are tested for their colloidal stability, drug encapsulation efficiency and particle size.
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 R. A. Youness, R. Kamel, N. A. Elkasabgy, P. Shao, and M. A. Farag, ‘Recent Advances in Tannic Acid (Gallotannin) Anticancer Activities and Drug Delivery Systems for Efficacy Improvement; A Comprehensive Review’, Molecules, vol. 26, no. 5, Art. no. 5, Jan. 2021, doi: 10.3390/molecules26051486.