Derya Görmüşoğlu

Master student (Department of Chemistry and Pharmacy, FAU)

Magnetoelectric and Ion-Doped Bioactive Nanocomposite Hydrogels for 3D-Printed Bone Scaffolds with Remote Stimulation and Drug Delivery

 

Supervisors: M.Sc. Andrada-Ioana Damian-Buda, Dr. Vicente Durán Toro, Prof. Dr. Danijela Gregurec (Department of Chemistry and Pharmacy),  Prof. Dr.-Ing. habil. Aldo R. Boccaccini

In collaboration with Prof. Danijela Gregurec’s Biointerfaces Lab, at FAU Department of Chemistry and Pharmacy, this project integrates magnetoelectric nanoparticles (MENs) and mesoporous bioactive glass nanoparticles (MBGNs) within multifunctional hydrogel matrices for 3D bioprinting and magnetically controlled drug delivery. MENs convert magnetic stimuli into local electric fields, allowing remote modulation of cellular activity [1]. MBGNs supply therapeutic ions and stimulate hydroxyapatite formation, while hydrogels provide a supportive, printable, and biodegradable matrix for cell growth [2]. Together, these systems aim to create magnetically responsive, bioactive scaffolds for tissue regeneration and cell stimulation.
[1] Gregurec, D.; et al. Hydrophobic-Phase Deposition of Barium Titanate on Cobalt Ferrite Nanoparticles from a Bimetallic Complex Precursor… ChemRxiv 2025, DOI: 10.26434/chemrxiv-2025-psk62.

[2] Damian-Buda, A.-I.; et al. Alginate–Gelatin–Xanthan Injectable Hydrogels Loaded with MBGNs and Essential Oils… Macromol. Biosci. 2025, 25 (2), 2500252. https://doi.org/10.1002/mabi.202500252.